Transferrin (Tf), a blood-plasma glycoprotein playing a key role in iron metabolism and ferric-ion delivery, binds specifically to transferrin receptor (TfR). Tf is covalently conjugated to the surface of iron oxide nanoparticles with amphiphilic polymer coating.

NP-AB-TF: Transferrin Conjugated Iron Oxide Nanoparticle

    • Amphiphilic polymer coating
    • Covalently conjugated transferrin for highly affinitive binding for transferrin receptor
    • High stability in water, buffers, cell culture media, and biological samples
    • Minimal non-specific interactions will biomolecules and cells
    • High capacity for loading hydrophobic molecules
    • MRI contrast enhancement capability
    • Selections of amine (-NH2), carboxyl (-COOH) or no surface active group